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December 2014

Volume 1 Issue 2

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Review Article
The cost effectiveness of brief intervention by primary health care workers to reduce alcohol related disease and injury in Vietnam

Christopher M Doran*, Nguyen Minh Tam, Nguyen Hoang Lan, Hue Tran, Peter Hill

This study examines the cost-effectiveness of early identification and brief advice for people with hazardous and harmful alcohol use in Vietnam. Two scenarios in which BI is financed by the government (BI-GOV) and non-government organisations (BI-NGO) were compared with current practice. Costs and health outcomes were measured over a 10 year period, referenced to 2006 and discounted at 3%. Cost-effectiveness was modelled using a multi-state and multiple cohort life table approach using a Vietnamese health sector perspective.

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Short Commentary
Hypothesizing Benefits of the Incorporation of Genetic Addiction Risk Score (GARSRX™Rx™) and Dopamine Agonist Modalities (DAM) in Clinical Addiction Medicine.

K. Blum, PhD, DE. Smith, MD, J. Femino, MD, AK.Roy, MD, T. Simpatico, MD, D. Inaba, Pharm D., G. Agan,BSc., JL.Fratantonio, Pharm D., M. Febo,PhD, F Fornari, PhD, M Hauser, MSc, D. Barh, PhD

We have entered the genomics era with hope for the future of medicine including Psychiatry. Understanding the role of DNA and polymorphic associations with brain reward circuitry has led to a new understanding of all addictive behaviors. We present here, a brief review of the role of both neurogentics and nutrigenomics as cornerstones that link more accurate genetic diagnosis and Dopamine D2 agonist therapy to induce dopaminergic activation.

 

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Research Article
15 Hz Repetitive Transcranial Magnetic Stimulation Over the Left Prefrontal Cortex Reduces Cocaine Craving

Ernestina Politi MD, PhD, Giampiero Bottero MD, Eugenia Fauci MD, Valentina Ferrari MD, Enrico Smeraldi MD

Recent studies support the association between addiction and the progressive alteration of cortical excitability, particularly focussing on the effect of chronic assumption of substance of abuse over the prefrontal cortex through the use of both cerebral stimulation and electroencephalographic techniques.

 

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Research Article
The Economic Benefit of Addressing Alcohol Harm in Rural Australian Communities Using A Multifaceted Approach

*Christopher M Doran PhD, Anthony P Shakeshaft PhD, Dennis Petrie PhD, Joshua Byrnes PhD, Ansari Abudeen

The aim of this research is to conduct a benefit-cost analysis of an Australian community-action approach to reducing riskyalcohol consumption and harm: the Alcohol Action in Rural Communities (AARC) project. The trial comprised 20 communities in New South Wales, Australia, that had populations of 5,000-20,000,were at least 100km from an urban centre (population ≥ 100,000) and were not involved in another community alcohol project. Communities were pair-matched and one randomly allocated to the experimental group. Thirteen interventions were implemented in the experimental communities from 2005 to 2009. The net economic benefit of AARC ranged from AUD $1,658,429 to $2,129,265. The cost of AARC was AUD$1,214,012, comprising intervention costs ($608,102) and additional hospital inpatient costs ($605,910).

 

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Research Article
Underage Drinking in the South of Italy: Alexithymia Attachment Expectancies of Alcohol and Binge / Heavy Drinking Behavior in Adolescents

Elisa Marcellino, Federico Tonioni, Daniela Altavilla, Paola Aceto, Massimiliano Luciani, Carlo Lai*

The hypotheses were that alexithymia and attachment will be positively associated with the alcohol expectancies and that alexithymia, attachment, and alcohol expectancies will predict the binge and heavy drinking behavior in adolescence. The 317 students (16-18 years old; male 148, female 169) completed the self-report scales: Toronto Alexithymia Scale 20, Inventory of Parent and Peer Attachment, My Alcohol Consumption and the Positive Drinking Expectancy Scale. The scores of alienation towards parents and the levels of externally-oriented thinking were positively associated with the levels of expectancies of alcohol (disinhibition, relief and social).

    

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